Sunday, January 25, 2026

2025 noble prize for health

Researchers have discovered the master switch that prevents the human immune system from attacking itself.

And they just won the Nobel.

The 2025 Nobel Prize in Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell, and Shimon Sakaguchi for their groundbreaking work on peripheral immune tolerance. 

While the immune system is a powerful defense against external pathogens, it requires precise regulation to avoid damaging the body's own organs. Sakaguchi first identified a specialized group of 'regulatory T cells' that act as a biological brake on immune responses. This discovery was completed when Brunkow and Ramsdell identified the FOXP3 gene as the master switch governing these cells, a finding initially made while studying a rare and fatal autoimmune disorder in children.

By revealing how the body maintains this delicate internal balance, these laureates have provided the foundation for a new era of medical treatment. Their work explains the biological origins of autoimmune diseases and has led to the development of therapies that are currently being explored to treat chronic conditions, improve organ transplant success, and even reprogram the immune environment around tumors to fight cancer. These discoveries represent a fund8amental shift in immunology, moving beyond simple defense to a sophisticated understanding of how the body governs its own cellular power.

source: Nobel Prize Outreach AB. (2025). The Nobel Prize in Physiology or Medicine 2025. Nobel Prize Press Release.

Thursday, January 8, 2026

#endsars- An experience

I have had my own share of NigeriaSARS @13.

In our house ehn, we love kids and I'm always the one bringing in kids we carry. So there's this little girl called Sharon that I started carrying and she was just 3 months old. Her mum drops her with us in the morning, goes off to wherever and comes pick her up at night. This continued for a year and the girl didn't even know her mum because she was never around. The Dad was even worse than the mum. I never knew what they did for a living and all I was after was just taking care of little Sharon. Was I paid? No.


When Sharon was 1, they decided to move away to a new house luckily enough for us all, I was on holiday and I decided to go with them. I stayed with them for a week and I left. Then I attended a boarding school and Sharon's mum always found a way to send provisions to my mum to give me in school even after they moved.

During one of my holiday, I was at my neighbour's house when my mum called at around 8pm that I should come back home immediately. I quickly left and on getting home, I met 3 men who asked my name, and I told them. They asked if I knew where Sharon's mum and Dad were, I told them no, I didn't and I haven't seen them for a while as I just got back from school. This men said I was lying and told me to get out and go into their car. My mum was about to object and they threaten to shoot her. She began to cry as I was taken away. Took me to one hotel to meet their boss who was drinking there, he told them to take me away if I didn't give them what they wanted. Mum kept calling me and crying, she called all our neighbors and thank God most where with the police. One of them spoke to the SARS and told them to take me to the police station.
They took me to the police station and when they saw that the police men there where all our neighbors who were waiting and asking them to let me go, they got angry, told the police men that I had to take them to their Sharon's house first before they'll let me go.
We got into the car again and I took them to the house but alas, no one was home. They started threatening me, telling me that I took them to the wrong house and I must know someone in that vicinity who Sharon's mum talk to. I told them that she introduced a lady to me as her sister and I took them to the lady's house.
They took both of us away and suddenly changed their mind about taking me home. That night, at around 10-11pm, they took us both to their office.
On getting there, one of them said that we should be taken to the Abattoir while another objected. They told me that Sharon's mum was a thief and they were looking for her, I told them I only carry Sharon and that's how I got to know them, I did not know what they do for a living besides she only told my mum she works in town as a banker that's why she leaves early and comes back late.
I slept in one of the office there, wrote my statement and by day break, I saw that those people were not humans. They caught some boys, broke their knee with an iron rod. One of them kept shouting that he was innocent and his wife just gave birth. Met a church member there who asked me what I was doing there, I narrated everything to him and he decided to help out. Dunno what he said or how he did it but they said my mum had to bail me else, I won't be released. Called my mum and she sent a family friend to come bail me with 10000 and that's how they let me go. I don't know what happened to the other lady they took.
Got home and met my mum still crying. She felt helpless. Our neighbors who were police men were already planning on coming there that afternoon if they refused to let me go........
SARS can be ruthless.
You don't have to wear dread, flashy clothes, or hold iPhone, drive expensive car, carry laptop before they harass you.

Copied

Schooling Children

Children’s vocabulary when they start kindergarten is an important predictor of academic success throughout their school.

 Therefore it is important to work on building their vocabulary, language and communication skills. 

To start with, introduce them to new words during their day-to-day activities.  e.g At the grocery store, you can explain to them that bread comes from a bakery and show them a bakery on the way home. 

Children often have an obsession with things, be it cars, birds or a stray cat. The next time your child is chatting about their obsession, throw in a few words that they have never heard before into the discussion.

Tuesday, April 22, 2025

A Pope's Death

 I am not a Catholic, but for decades - especially since reading David Yallop’s book, THE POWER AND THE GLORY and Dan Brown’s novel, ANGELS AND DEMONS - I have been intrigued by the Catholic Church.

One of the most fascinating Catholic events is the death of a Pope.


When a Pope dies, the world literally stops for a while and the major networks cease their originally scheduled programming for hours, if not days.


Incidentally the last time a sitting Pope died was on 2 April 2005, which means that many have never witnessed the traditions and ceremonies that surround the death and funeral of a Pope. 

When a Pope dies, the entire country, the Vatican City falls into an eerie silence. Bells toll somberly across Rome and the great bronze bell of St. Peter’s Basilica sounds its heavy, sorrowful note. And within the thick, ancient walls of the Apostolic Palace, an ancient and sacred ritual begins — one unseen by the public.


The first thing that happens is that a Cardinal, known as the Camerlengo is summoned. It is the Camerlengo that pronounces the Pope dead, he announces his death to the world, and he administers the Holy See during the interregnum, until a new Pope is elected. More on that later.


Standing solemnly at the Pope’s bedside, the Camerlengo must perform a ritual that is as theatrical as it is solemn and grave. He calls the Pope’s baptismal name three times. In the case of Pope Francis, the Camerlengo must have said, “Jorge, Jorge, Jorge”. Once no response is received, the Camerlengo declares the Pope dead. As we learnt from ANGELS AND DEMONS, that’s it. No autopsy.


Next, the Camerlengo solemnly removes the Fisherman’s Ring — the signet worn by the Pope — and ceremoniously destroys it, usually by hammering it or cutting it with shears. This ritual symbolizes that the earthly reign of the man who once ruled Christendom is well and truly over.


Following the death of the Holy Father, the Holy See enters a time of Sede Vacante— the "empty seat." The papal apartments are sealed, literally locked and taped shut. The Swiss Guard — the colorful sentinels you must have seen on TV — redouble their watch.


Under Catholic rules, a Pope’s burial should take place between four and six days after his death. But there is a nine-day period of mourning known as the novendiale. For those nine days, the Church mourns, and the city of Rome transforms into a river of black and purple.


Behind the scenes, the Pope’s body is prepared for public viewing and then laid in state before thousands of mourners — the faithful, who move past his bier with heads bowed, at St. Peter’s Basilica. There is also the procession across St. Peter’s square.


Meanwhile, behind the scenes, a quiet but intense political ballet begins among the Church's Cardinals. In whispered conversations in hidden corridors, alliances form and fade. Who will be worthy to take his place and bear the mantle of the first Bishop of Rome, Pope Peter I?


Because the Church of Christ must march on and the gates of hades cannot prevail, then comes the centuries old process of the election of a new Pope, the Conclave. The Conclave is the oldest historical method of electing the Pope. It involves different rounds of voting until a Pope emerges having won two-thirds majority.


The Conclave takes place typically between 15 to 20 days after the death of a Pope. Inside the Sistine Chapel, behind marble walls and beneath Michelangelo’s frescoes, 120 cardinals — those under the age of 80 — gather in red robes to select the next Pope.


With almost theatrical drama, the Cardinals, with no phones or connection to the outside world. walk in solemn procession into the Sistine Chapel, chanting the ancient prayer Veni Creator Spiritus ("Come, Creator Spirit"), invoking the Holy Spirit to guide their minds and hearts.


The heavy doors of the Sistine Chapel are shut with the words "Extra omnes!" — "Everyone out!" Only the Cardinals and a few support staff remain. The world is cut off. The voting begins.


Each Cardinal writes the name of his chosen candidate on a ballot, folds it, and walks, to the altar under Michelangelo’s towering Last Judgment. There, he slides it into a chalice and utters the words: "Testor Christum Dominum qui me iudicaturus est": "I call Christ the Lord to witness that my vote is given to the one I think should be elected."


After each round of voting — known as a scrutiny — the ballots are burned in a special stove. Chemicals are added: black smoke means no Pope has been chosen; white smoke signals there is new Pope. All this while, the crowd wait in St. Peter’s Square, staring up at the thin chimney. Every wisp of smoke is greeted with a wave of gasps and murmurs from the crowd.


The shortest Conclave is history is generally considered to be the October 1503 papal conclave which lasted for less than 10 hours. There was also the 1 – 2 March 1939 Conclave which saw the election of Pope Pius XII on his 63rd birthday to replace Pope Pius XI. The longest Conclave lasted for three years. Not to worry, modern Conclaves now last only a few days.


When a Cardinal finally receives two-thirds of the votes, bells will ring within the Sistine Chapel and the chosen Cardinal is escorted outside and asked the historical question - "Do you accept your canonical election as Supreme Pontiff?"


If the Cardinal accepts his election - and who would not? - he is immediately asked to take a new name. That is how Cardinal Jorge Mario Bergoglio became Pope Francis; Cardinal Joseph Ratzinger became Pope Benedict XVI and Cardinal Karol Józef Wojtyła became Pope John II.


But before he is dressed in his papal garment, he will be led to the “Room of Tears” where he will have a moment alone to reflect on the burdens of his new position. It is actually in the room of tears that he changes into his papal vestments


Next, the new Pope is dressed in white papal garment. Fun fact: the papal garment is prepared in three sizes since no one knows beforehand who will be chosen as Pope. Once dressed, the Pope returns to the Sistine Chapel to be greeted by the Cardinal, each kissing his hand in reverence.


Outside, the pure unmistakable white smoke appears, to be greeted by the triumphant tolling of the bells of St. Peter's Basilica and a roar of the crowd. 


And on the central balcony, the Senior Cardinal Deacon appears in red and gold, raises his arms to silence the crowd and declares to the world, "Annuntio vobis gaudium magnum: Habemus Papam!" ("I announce to you a great joy: We have a Pope!")


Adapted from: Orji Agwu Uka

Sunday, June 25, 2023

Cucumbers

 FACTS ABOUT CUCUMBERS YOU MUST KNOW

1. Cucumbers contain most of the vitamins you need every day, just one cucumber contains Vitamin B1, Vitamin B2, Vitamin B3, Vitamin B5, Vitamin B6, Folic Acid, Vitamin C, Calcium, Iron, Magnesium, Phosphorus, Potassium and Zinc.

2. Feeling tired in the afternoon, put down the caffeinated soda and pick up a cucumber. Cucumbers are a good source of B vitamins and Carbohydrates that can provide that quick pick-me-up that can last for hours.

3. Tired of your bathroom mirror fogging up after a shower? Try rubbing a cucumber slice along the mirror, it will eliminate the fog and provide a soothing, spa-like fragrance.

4. Are grubs and slugs ruining your planting beds? Place a few slices in a small pie tin and your garden will be free of pests all season long. The chemicals in the cucumber react with the aluminum to give off a scent undetectable to humans but drive garden pests crazy and make them flee the area.

5. Looking for a fast and easy way to remove cellulite before going out or to the pool? Try rubbing a slice or two of cucumbers along your problem area for a few minutes, the phytochemicals in the cucumber cause the collagen in your skin to tighten, firming up the outer layer and reducing the visibility of cellulite. Works great on wrinkles too!!!

6. Want to avoid a hangover or terrible headache? Eat a few cucumber slices before going to bed and wake up refreshed and headache free. Cucumbers contain enough sugar, B vitamins and electrolytes to replenish essential nutrients the body lost, keeping everything in equilibrium, avoiding both a hangover and headache!!

7. Looking to fight off that afternoon or evening snacking binge? Cucumbers have been used for centuries and often used by European trappers, traders and explores for quick meals to thwart off starvation.

8. Have an important meeting or job interview and you realize that you don't have enough time to polish your shoes? Rub a freshly cut cucumber over the shoe, its chemicals will provide a quick and durable shine that not only looks great but also repels water.

9. Out of WD 40 and need to fix a squeaky hinge? Take a cucumber slice and rub it along the problematic hinge, and voila, the squeak is gone!

10. Stressed out and don't have time for massage, facial or visit to the spa? Cut up an entire cucumber and place it in a boiling pot of water, the chemicals and nutrients from the cucumber will react with the boiling water and be released in the steam, creating a soothing, relaxing aroma that has been shown the reduce stress in new mothers and college students during final exams.

11. Just finish a business lunch and realize you don't have gum or mints? Take a slice of cucumber and press it to the roof of your mouth with your tongue for 30 seconds to eliminate bad breath, the phytochemicals will kill the bacteria in your mouth responsible for causing bad breath.

12. Looking for a 'green' way to clean your taps, sinks or stainless steel? Take a slice of cucumber and rub it on the surface you want to clean, not only will it remove years of tarnish and bring back the

shine, but is won't leave streaks and won't harm you fingers or fingernails while you clean.

13. Using a pen and made a mistake? Take the outside of the cucumber and slowly use it to erase the pen writing, also works great on crayons and markers that the kids have used to decorate the walls!!

Saturday, March 11, 2023

Diary

So my baby toilet trained. .
My son now draws

Diary

4th oct
Its the first sunday of the month and we are positive.

Day wanted to start low, but God was showing us something.
Gratitude is everything. My phone screen got bad as I had lay on it and I felt troubled. Like Lord, expenses? But I looked to the bright side and said 'it will teach me a lesson not to put my phones on my bed again.

The 5am club gang. I now stop phone palava by 8pm. Discipline is what we need for success! All glory to God.

 I just discovered depression weight loss does nothing on your abs.

On my second 3 weeks abstinence from rice, bread, spag , milk and cocoa and byproducts.
 

Wow. Glory to God. Its Sunday, n I can't wait to sing onto d Lord joyfully! 12-3-23